How a hCG injection stimulates ovulation and why an egg is released. Will an HCG injection help you get pregnant?

After an HCG injection, when does ovulation occur? For what purpose is it made? The specialist recommends an injection designed to stimulate ovulation when a woman has problems with egg maturation. For each patient, selection occurs individually, at the moment when the cause of such a condition is established, after passing all laboratory tests and undergoing a mandatory diagnostic examination.

The main methods that help determine the reason why eggs do not mature in the ovaries are:

• hormone analysis;
• undergoing continuous ultrasound examination;
• Diagnosis requires several cycles in a row in order to correctly draw conclusions regarding the woman’s condition and then prescribe treatment.

The main factor that affects a woman’s ability to get pregnant and carry a child to term is the ovulation process. This is the period when the egg gets the opportunity to leave the shell and, having passed through the fallopian tube, be fertilized. Pregnancy will not occur if the egg is unable to break through the follicle membrane and come out of it. A hormone called human gonadotropin is responsible for this.

Its function is to influence the corpus luteum and do this until the fertilized egg attaches to the uterine cavity. Next, the production of hormones occurs in the placenta, which is responsible for supplying progesterone and estrogen to the woman’s body. Quite often, ovulation, as well as the production of hormones, does not occur. Therefore, the doctor prescribes an injection of hCG, which is very important in the first trimester of pregnancy.

There are different doses of hCG, which are selected individually for each patient.

Different drugs are prescribed for injection, which are selected specifically for each woman, depending on the existing indications. Before the procedure, patients are interested in questions about how long it will take for ovulation to occur after an hCG injection and how quickly the amount of hormones will increase after administration.

Doctors note that women, by determining whether ovulation is occurring or not and doing the test almost immediately (usually on the second or third day), receive positive results. But this does not indicate that ovulation is occurring. Therefore, to ensure the reliability of the result, the test is recommended to be carried out only on the third day after the administration of the hormone.

After an HCG injection, you should wait for the moment when ovulation occurs, as well as for an increase in the amount of the desired substance in the woman’s body. Doubling can occur once every 3 days. A very high level of progression is observed in the first trimester, which contributes to increased production of estrogen and progesterone.

The hCG injection after ovulation must be monitored in order to properly monitor the growth of hormones. Such monitoring should be done using both special tests and ultrasound. During an ectopic pregnancy, human gonadotropin can also manifest itself, but has other indicators and behavioral tendencies.

It is also worth remembering that the results of hCG injection can be very different, for example:

• the onset of ovulation after 24-36 hours;
• perhaps it will come a little later;
• won't come at all.

Indications and contraindications

Indications for an injection are factors such as:

1. The need to stimulate the yang cell.
2. Prevent the follicle from shrinking if the egg is released from it. Otherwise, the membrane may shrink and a cyst may appear in its place.
3. It is necessary to preserve the vital activity of the corpus luteum. To support it, you need to give an appropriate injection.
4. If there is a slow development of the placenta, it does not form and does not secrete the required amount of hormones.
5. To maintain pregnancy and avoid miscarriages.
6. Before performing in vitro fertilization.

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Contraindications for hCG injection include:

• cancer, especially ovarian cancer;
• pituitary tumor;
• early menopause;
• breastfeeding a child;
• blood clots in blood vessels or a genetic predisposition to this;
• uterine tubal obstruction;
• hypothyroidism, that is, a long-term lack of hormones in the thyroid gland;
• individual intolerance to the components of the drug.

Time of ovulation after injection

The doctor decides which drug to choose. These may be the following types of medications that contain human chorionic gonadotropin:

• Clomiphene;
• menopausal hCG;
• recombinant beta-follicle-stimulating hormone;
• Humegon;
• Pergonal;
• Menogon.

In order to determine which drug a particular woman needs, the gynecologist must carefully examine the tests for the level of estradiol and luteinizing hormone.

The injection is prescribed only on the third to fifth day of the menstrual cycle; the initial dosage of the medication is chosen depending on hormonal parameters. You cannot determine the volume of the drug yourself; it is used only after a doctor has prescribed a dosage regimen. Usually they give an injection of hCG 5000 or 10000 units, which depends on the indicators of the woman’s body.

Stimulation is carried out in cycles, under the careful supervision of a gynecologist, with measurement of basal temperature.
After the first injection stimulation has been done, on the 5th (maximum 7) day, you need to undergo a control ultrasound examination. Its essence is to determine the cervical number, the amount of estradiol, and endometrial growth.

If there is no reaction, then the dose can be increased and changes in indicators will be monitored by ultrasound after 1 day. Folliculogenesis is considered dynamic if the follicle increases in size by 2 mm during the day, and the number of cervical numbers increases by 2 units. within 24 hours. If this is the case, then the dose of the drug does not change. Its amount can be reduced by one ampoule when the indicators increase very quickly.

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Folliculogenesis - the active phase - lasts for 5 days and can end on the tenth to twelfth day after ovulation stimulation begins.

When the membrane is 18-20 mm, which is detected during a follow-up examination, then ultrasound should be performed every day. In this case, the dose of the hormone is again reduced so that the follicle does not demonstrate independent behavior. When the number becomes 12 units, then the injections stop, and a day later the last injection is given - an ovulatory dose of human chorionic gonadotropin. A control measurement is carried out after 2-3 days to confirm ovulation.

All a woman’s sensations are associated with the transformations that occur in her body throughout the menstrual cycle. It is enough to observe your well-being and mood for several months in a row, and you can know when ovulation occurs. At first, you will need to keep a basal temperature chart to confirm your feelings with natural data.

A new cycle begins from the first days of menstruation. Then, under the influence of hormones that the ovaries produce, eggs are born in the follicles. Over the course of a week, they all develop in the same way. At the same time, the ovary increases slightly in size. After a few more days, one of the follicles is several millimeters ahead of the others in growth. Becomes the main one. In general, the process of follicle maturation takes from 12 to 16 days from the beginning of the cycle. After this time, the follicle leaves the ovary and bursts. An egg appears ready for fertilization. The remains of the follicle come out along with vaginal discharge. The moment the egg is released from the follicle is called ovulation.

The rupture of the follicle, the entry of the egg into the uterine cavity, is accompanied by minor painful sensations, and particles of blood appear in the discharge. As a rule, the unusual sensations of ovulation last only a few days and women do not pay much attention to them. But even those who do not know what ovulation is can note that in the middle of the cycle there are several days when the discharge becomes like egg white and increases in quantity. And in some cases, during ovulation, pink streaks and droplets of blood are visible in them. At the same time, especially sensitive women or women with less than adequate hormonal levels notice significant changes in their feelings and behavior.

How to determine ovulation

The process of the egg leaving the follicle remains invisible to many women. In principle, this is how it should be when everything is normal. If physiologically it was built differently, there would be no unplanned pregnancy and problems with conception. But no, you need to conduct a serious study of your body. What effort is required?

The simplest method that allows and can be used at home is measuring basal temperature. A woman must adjust to a certain sleep and wakefulness schedule, adjust her diet, and eliminate bad habits. An ordinary thermometer is used as a tool. You will need a notebook where you will record every day, sensations, life events, and well-being. Then you can view the ovulation period. You will have to measure every day at the same time, without getting out of bed. The sleep interval should be at least 6 hours. If a woman gets up at night, the temperature will not reflect a true picture of the processes occurring in the body. Basal temperature is measured in the vagina or rectum. The latter option is considered more accurate.

What factors influence the temperature indicator?

• Alcohol;
• strong tea, coffee;
• sexual intercourse;
• disease of internal organs;
• Acute respiratory infections and flu with fever;
• nervous stress, tension;
• physical fatigue;
• taking pills.

A record should be kept every day, a graph should be drawn according to the data received. The basal temperature in the first half of the cycle, before ovulation, remains below 37 degrees Celsius. 2 days before ovulation there is a decrease of 3-4 degrees. Then a sharp increase of 5-6 degrees. Up to approximately 37.5–37.8 degrees. This is ovulation. After 1–2 days, the temperature drops again by several degrees. If there is pregnancy, it does not fall below 37.

To determine the days of ovulation in your cycle, you should conduct research over a period of 6 months. In women under 30 years of age, 2 cycles are allowed when there is no ovulation, which is considered normal. After 35 years, there are up to 6 cycles a year without ovulation.

What are the sensations during ovulation?

You can determine ovulation by the discharge and feel it. First of all, changes in well-being are associated with hormones. On the eve of ovulation, estrogen increases, and immediately after it, the majority is progesterone. What changes occur in the body during ovulation?

In addition, during ovulation a woman feels a surge of energy, a good mood, an increase in libido, and sex brings the greatest pleasure.

All sensations during ovulation are individual. Sometimes a woman does not experience anything like this at all, and the suspicion of ovulation and all processes disappear due to discharge. They become viscous, transparent, in abundant quantities, and odorless.

Feelings after ovulation

Sometimes a woman learns about the release of an egg from the follicle only after ovulation has ended. Changes in sensations are associated with increased progesterone levels. After which the woman becomes less active in behavior, taste preferences change, anxiety and irritability appear. The first changes after ovulation concern the psycho-emotional sphere. Physical sensations after ovulation are very noticeable in chronic gastrointestinal diseases. Then there may be stomach pain and intestinal dysfunction. Basically, nothing unusual happens. If ovulation causes pain in a woman's ovarian area, she may feel relief afterwards. Which means that the follicle has burst and the egg has entered the uterine cavity.

Feelings after an HCG injection

If the process of follicle maturation in the ovary does not occur naturally, ovulation is stimulated. HCG injection is used in complex therapy of infertility. It is used for artificial insemination of a woman, during the IVF process. However, in this case, it is problematic to feel the process of follicle rupture. Just like the sensations themselves during ovulation are deceptive. Due to the fact that a woman is prescribed hormone therapy, everything that happens in the woman’s body will be associated with their influence. The process of follicle maturation in a woman is monitored using ultrasound. Then it becomes clear when the egg ends up in the uterus. The discharge after an hCG injection is also ambiguous. In this case, you should not focus on your own feelings and natural secretions.

In the first half of the cycle, the ovary increases in size due to the maturation of the follicles; in the second half, the uterus increases in size. The endometrial layer thickens. The uterus is preparing to receive a fertilized egg and develop pregnancy. Based on this, before ovulation there may be minor discomfort in the ovarian area, and after ovulation - in the area of ​​the uterus. Bloating, indigestion, and changes in emotional background can be observed on any day of the cycle. And the processes of the menstrual cycle are not always to blame.

The need to stimulate ovulation must be clearly justified. Most experts believe that an hCG injection to stimulate ovulation can be given no more than 6 times during the entire reproductive period of a woman’s life. There are many contraindications to such a procedure, so only a doctor can formulate all the expected advantages and possible disadvantages.

This procedure is used in modern reproductology in cases where the body of a man and a woman, under certain conditions, is capable of fertilizing germ cells; in the future, the woman may experience a desired pregnancy. This is a fairly effective technique, since a positive effect is observed in 3/4 of cases.

Stimulation can be carried out by conservative (injections, tablets) or surgical (wedge resection, laser cauterization) methods. The method is selected individually depending on the health status of the particular patient and the problem that caused infertility. Sometimes the hCG injection and ovulation precede the in vitro fertilization procedure.

What happens during stimulation with the egg?

Under normal conditions, on a certain day of the cycle (the follicle ruptures), it moves from the ovary along the fallopian tube into the uterine cavity. If at this moment the male reproductive cell fertilizes the female, pregnancy occurs. The fertilized egg is implanted into the endometrium and undergoes further development. This is facilitated by the normal functioning of the corpus luteum in the ovary.

Ovulation after an injection of hCG (or another method of stimulation) can be activated if the follicle does not rupture, but begins to decrease in size along with the egg, that is, transform into a cyst. In addition, hCG injection is indicated in the following cases:

• there is a slow development of the placenta, which does not correspond to the gestational age;
• for the full functioning of the corpus luteum (in the early stages of gestation);
• if there is a threat of spontaneous termination of the current pregnancy or previous episodes of miscarriage.

It must be emphasized that ovulation can occur after stimulation with human chorionic gonadotropin if the attending physician has correctly established the cause of the couple’s infertility.

When ovulation stimulation is contraindicated

There are situations when ovulation simply cannot occur after an injection of hCG (or any other stimulation option). Such conditions of the female or male body are a contraindication to this procedure:

• a certain age of the patient (beginning of menopause);
• obstruction of the fallopian tubes;
• local (in the reproductive organs) or systemic infectious processes;
• unsatisfactory spermogram of the sexual partner;
• pathology of the thyroid gland;
• imbalance of male and female sex hormones, as well as the pituitary gland;
• tumor processes of the reproductive sphere of benign and malignant origin, especially hormone-dependent;
• increased susceptibility to thrombosis;
• allergic predisposition to drug components.

In all these cases, it will be necessary to use other methods of treating male and female infertility. For example, if the “culprit” of a couple’s infertility is a young man, that is, male infertility is diagnosed, no stimulation of ovulation will bring positive results.

What examinations need to be completed

Before stimulation, it is necessary to find out in detail when ovulation occurs, and whether it occurs at all. A full examination includes the following aspects:

• spermogram of the sexual partner;
• examination by a family doctor (local therapist);
• hormonal panel (male and female sex hormones);
• screening studies excluding hepatitis with parenteral transmission, human immunodeficiency virus, infectious diseases of the genital tract (gonorrhea, syphilis, trichomoniasis, candidiasis, ureaplasmosis);
• hysteroscopy to assess tubal patency;
• Ultrasound of all pelvic organs.

Before this happens (no matter which method is chosen), a woman must adhere to a healthy lifestyle, eat well and take multivitamin complexes.

Main stages of drug stimulation

The stimulation procedure takes place under the dynamic control of a doctor using ultrasound. After the completion of menstrual bleeding (no earlier than 8-10 days), the first ultrasound examination is performed, the condition of the ovaries is assessed for egg maturation. There is no clear answer to the question of how many days the stimulation will take place, since an individual protocol is drawn up for each patient.

Stimulating follicle rupture

After isolating the dominant follicle (that is, the one that is large in size, about 17-18 mm and will rupture first for subsequent fertilization), an ultrasound examination is carried out 2-3 days before the embryo is diagnosed in the uterus. A woman should not worry about such frequent examinations. Ultrasound diagnostics is absolutely harmless both for the female body and for the unborn child.

When ovulation approaches, that is, the dominant follicle reaches its maximum size, but its rupture is not observed, an injection of hCG is necessary (the dosage is selected individually), which stimulates the rupture of an already formed follicle.

Usually 24-28 hours after the injection, the dominant follicle ruptures. The woman feels discomfort from the rupture, but mandatory ultrasound monitoring is required.

Once confirmation is received, daily sexual intercourse or a planned IVF procedure is recommended.

Stimulating follicle maturation

According to ultrasound data, it can be established that follicles are forming in the woman’s ovaries, but none of them can be called dominant, since they are of insufficient size. In this case, agents are required that affect follicle-stimulating and luteinizing hormones and, accordingly, the formation and maturation of the follicle in the ovary. The most widely used products are those based on clomiphene (“Clostilbegit”).

Starts from days 5 to 9 of the menstrual cycle. A control ultrasound examination is required. At the same time as clomiphene, the woman takes estrogen-containing drugs (Proginova). Next, an injection of hCG 5000 (or a higher dosage) is applied. In this way, both the process of maturation of the follicle and its subsequent rupture with the release of the egg are stimulated. It is clear that the ovulation test after an hCG injection will be positive, but a dynamic ultrasound is still necessary.

To maintain pregnancy, progesterone (Utrozhestan or Duphaston) is often used to stimulate and facilitate the functioning of the corpus luteum.

An HCG 10,000 injection (or a lower dose) can only be used once during the entire cycle. Repeated episodes of stimulation only lead to depletion of the ovaries, and not to the onset of the desired pregnancy. Repeated episodes of hCG injections are permissible only during a developing pregnancy, since chorionic hormone is necessary for its preservation.

There are also other ways to stimulate ovulation: using the drug Gonal (instead of Clostilbegit), various surgical interventions. Only a qualified specialist in the field of reproductology will be able to select the only and most effective infertility treatment option for a particular woman.

Human chorionic gonadotropin is a hormone necessary for the fertilization of an egg and maintenance. Sometimes a woman's body produces too little hCG, which prevents her from becoming pregnant. Then synthetic analogues of the hormone are used in the form of an injection.

HCG preparations are made from proteins in the urine of pregnant women. The hormone stimulates the synthesis of progesterone and estrogen - the main hormones that help form the corpus luteum and attach the embryo to the wall of the uterus, and then preserve the fetus until the placenta forms.

The drugs are available in the form of an injection solution and have the following names: Pregnil, Menogon, Novarel. The injection is given in the abdominal area with a syringe with a short insulin needle.

HCG injections stimulate the ovulatory process and are used for the following pathologies:

• Impaired ovarian function resulting from a malfunction of the hypothalamus and pituitary gland.
• Dysmenorrhea (menstruation accompanied by severe dizziness and weakness).
• Infertility, which is anovulatory in nature. That is, there is no dominant one.
• Insufficient level of functioning of the corpus luteum.
• Miscarriage (constant miscarriages or frozen pregnancies).
• Preparation for in vitro fertilization.
• Maintaining pregnancy.

There are contraindications for the use of such stimulation:

• Various tumors, cysts in the ovaries.
• Early menopause.
• Lactation.
• Obstruction of the fallopian tubes.
• Diseases of the adrenal glands.
• Tendency to thrombosis.
• Individual intolerance.

Important! For patients with heart and kidney failure, hormones are prescribed only after a thorough examination!

HCG injection 10000 for stimulation

If a woman has impaired egg maturation functions, ovulation does not occur. The reasons for this are: polycystic disease, tumors, prolonged stress. The following situations are usually observed:

• The follicles do not mature at all.
• The follicles do not mature completely.
• The follicle matures, but the egg does not leave the corpus luteum.

The hCG injection is designed to help the formation of the follicle and stimulate the release of the egg.

Before using the hormone, a woman undergoes examination:

• Tests for hormone levels.
• Pipe patency examinations.

The hormone is administered when the doctor has determined the development of a dominant follicle on an ultrasound scan at a dosage of 1500-5000 units to stimulate its growth. To stimulate super ovulation in preparation for IVF, hCG is administered once in a dose of 10,000 units.

Ovulation should occur 24-36 hours after the injection. The process is monitored using ultrasound. If ovulation does not occur, then the amount is increased in the next cycle. The exact dosage is determined by the doctor for each specific case.

Important! Self-prescription of hormone therapy is prohibited, as this can lead to serious health consequences.

During ovulation

After the follicle bursts and the egg is released, to further maintain its vital activity and ability to fertilize, the doctor prescribes hCG injections.

Injections are given on days 3, 6 and 9 after ovulation at a dosage of 5000 units. This is necessary to maintain the corpus luteum and help implant the embryo.

During pregnancy

When pregnancy occurs, hCG is administered to prevent miscarriage or miscarriage.

Indications for this are:

• Risk of miscarriage.
• A sharp drop in hormone levels.

The hCG level is checked over time, since low levels may occur in the early stages, then they increase.

Important! Before the injection, it is necessary to perform an ultrasound to exclude ectopic pregnancy.

If the pregnancy is intrauterine, then to preserve it, 10,000 units of the drug are first administered, then 5,000 units twice a week. Treatment can last from 8 to 14 weeks, depending on the patient’s condition and hormonal levels. At the same time, Duphaston is prescribed to maintain progesterone levels.

How long will it take to ovulate?

Usually occurs 24-36 hours after administration of the hormone. During this time, for pregnancy to occur, sexual intercourse must occur every day.

Ovulation does not always occur after the injection; sometimes the corpus luteum continues to grow and turns into a cyst. Also, stimulation does not guarantee the onset of your own ovulation in the following months.

Thus, the hCG injection is a one-time stimulation procedure, and not a treatment for infertility.

When to take the test

The level of the hormone increases already on the first day after the injection, so it makes no sense to carry out ovulation tests within three days, as they will be false positive.

You need to check the onset of ovulation 3 days after the procedure.

When to test your hCG level

When pregnancy occurs, hCG levels begin to rise. A strong decrease (20%) indicates serious problems:

• Risk of miscarriage.
• Ectopic pregnancy.
• Delayed fetal development.
• Placental insufficiency.

To identify these pathologies, an ultrasound scan is necessary before starting hormonal treatment.

Normally, the hormone level constantly increases until the 11th week, then gradually decreases and remains unchanged throughout the entire period of gestation. For an accurate diagnosis, it is necessary to take repeated tests in the same laboratory.

HCG norms in honey/ml:

• Non-pregnant - 0-5.
• 1-2 weeks - 25-155.
• 3-4 weeks - 150-4800.
• 4-5 weeks - 2500-82000.
• 5-6 weeks - 23000-150000.
• 6-7 weeks - 30000-230000.
• Week 7-10 - 21000-290000.
• 11-14 weeks - 6000-100000.
• 16-21 weeks - 4000-80000.
• Weeks 21-39 - 2700-76000.

The first increase is recorded after 11 days of conception, the level doubles every 48 hours. At the level of 1000 units, the fertilized egg is visualized during ultrasound. To confirm the normal course of pregnancy, tests are performed every two days. Indicators may be above normal if:

• Multiple pregnancy.
• Gestose.
• Diabetes mellitus.
• Down syndrome.

This may also indicate an incorrect determination of the gestational age.

Before donating blood for the hormone, you must meet certain conditions:

• Take the test at the same time.
• Do not drink alcohol or smoke.
• Stop taking medications.
• Avoid physical activity.
• For several hours you should not take food or liquids other than water.

Possible complications

A hormone injection is an intervention in the natural processes of the body. Therefore, the following side effects often occur:

• Ovarian cyst.
• Vein thrombosis.
• Ascites (accumulation of fluid in the abdominal cavity).
• Hyperstimulation syndrome, which causes breathing problems, palpitations, abdominal pain, and dropsy.

Individual reactions may also occur in the form of nausea, vomiting, indigestion, pain in the lower abdomen and lower back, mood swings, and depression. These symptoms disappear after treatment ends.

Important! Hyperstimulation syndrome requires urgent medical attention and is treated in a hospital.

An HCG injection is a necessary support for ovulation and subsequent pregnancy. It is prescribed if a woman does not produce the hormone in sufficient quantities for some reason.

The dosage and regimen of use are chosen by the doctor, depending on the goals and health status of the woman. Typically, pregnancy after such stimulation occurs in the first two months. It should be remembered that the hCG injection is not a means of treating infertility, but a one-time stimulation.

You might find the following video useful:

- a hormone produced by the embryo after its attachment to the endometrium. It promotes the normal progression of pregnancy and ensures its smooth course. The main functions performed by the hormone are:

• Stimulation of the functioning of the corpus luteum. As a result, a sufficient amount of progesterone is provided, which remains the main substance that supports the development of pregnancy.
• Activation of growth and formation of the placenta, due to which contact between mother and child occurs.
• General control of metabolic processes in the body of a pregnant woman and fetus.

Considering the above functions of hCG, it becomes obvious that it is one of the main regulators of normal gestation. That is why its synthetic analogue is used in medicine to increase the chance of getting pregnant and prevent a number of pathological conditions. An injection of human chorionic gonadotropin can help you conceive and carry a healthy baby. However, everything depends on the specific circumstances of each individual case.

The standard determination of pregnancy occurs by using a classic pharmacy test. When the urine of a pregnant woman gets on it, the treasured 2 stripes appear on the tablet, which confirm the fact of the development of a new life in the womb.

The chemical reaction is based on interaction with the hormone in the urine. An alternative is to test the blood for the presence of a bioactive substance. In the absence of pregnancy, there is very little or no hormone in the body, however, if conception occurs, the hormone will begin to sharply increase its concentration in the blood. For the study, venous blood is used, in which hCG itself is looked for. The first positive results usually appear on days 7-10 in the blood and on days 10-14 in the urine.

Does an HCG injection affect the chance of getting pregnant?

Considering the functions of the hormone, as well as its fairly widespread use in medicine, women often ask: “Should we expect pregnancy after an hCG injection?” To answer, you need to understand a little more about the features of its application.

The hormone injection actually helped more than one woman get pregnant. However, there are only a limited number of situations in which it is effective.

HCG injections are prescribed for:

• Continued functioning of the corpus luteum. If it is insufficient, the endometrium may be inferior and the uterus will not be ready to accept the fetus. HCG changes this situation for the better.
• To speed up the process of placenta formation.
• To stimulate ovulation. This is what hCG is most often used for.
• To prepare for in vitro fertilization.

Considering the goals pursued by doctors, a number of indications for the use of hormone injections can be identified:

• Insufficient functional activity of the corpus luteum.
• Infertility caused by anovulatory menstrual cycle.
• Habitual miscarriage.
• High risk of miscarriage.
• As part of the process when using a variety of assisted reproductive technologies.

In all these situations, the use of hCG injection will be justified. This is confirmed by the many years of experience of doctors and reviews of those who have been helped by such an injection to become pregnant.

How is hCG used?

If a representative of the fair sex experiences anovulatory infertility, then an hCG injection may be one of the ways to solve the problem. It will also help those who, for one reason or another, have a hormonal imbalance, which leads to insufficient maturation of the follicles in the ovaries.

Those women who could not get pregnant for a long time note the positive effect of gonadotropin. Often, even with the progression of anovulatory infertility, it was possible to successfully conceive a child.

If the hormone is used during pregnancy planning, then a single injection of hCG 10,000 is considered standard. This dose is prescribed for a reason. Before the actual injection, an appropriate preparatory stage is carried out, which includes the use of hormones to stimulate follicle growth. Only after they develop and the dominant follicle reaches a size of 20-25 mm, can an HCG injection be used. This is usually days 14-20 of the cycle. The size of the follicle is monitored using ultrasound.

This procedure stimulates ovulation, the follicle ruptures, and the mature egg begins its journey towards sperm. HCG in this case “helps” natural conception occur. Typically, ovulation occurs 12-36 hours after the injection. Therefore, to achieve the desired result, it is necessary to actively try to conceive a child during this period of time. In most cases everything goes well.

Sometimes, to stimulate ovulation, it is enough to give an injection of hCG 5000. However, you need to understand that only the attending physician should calculate the dose. He will be able to comprehensively assess the patient’s condition, her hormonal balance and prescribe the appropriate amount of hCG.

The most popular drugs:

• Gonal (also Gonal F);
• Chorionic gonadotropin;
• Puregon;
• Menogon.

After successful conception, progesterone is additionally prescribed to maintain pregnancy.

What will a blood test show after an hCG injection?

Many women are interested in when they can perform an ovulation test after an hCG injection, and whether it is worth doing it at all. Basically, doctors recommend monitoring the process of the release of the egg from the follicle using ultrasound. However, if you want to use the appropriate tests, then they should be carried out virtually every day after the injection itself to monitor ovulation.

The dynamics of the increase in hCG in the blood after the intended act of conception will help determine its success. It is reasonable to do a pregnancy test after an hCG injection after 1-2 weeks. It takes approximately this long for a fertilized egg to begin to synthesize its own hCG. If you carry out diagnosis earlier, you can get a false-positive result, which is due to the preliminary administration of the drug in the form of an injection. In any case, you should consult your doctor to receive appropriate recommendations.

Individual reviews

Examples include reviews from visitors to one well-known clinic who were given an hCG injection (the survey was conducted anonymously, names have been changed):

• Anna: “At first I was stimulated with Clostilbegit. In the 1st cycle, the follicle reached 18 mm, but did not rupture. On the second attempt it was 19 mm, and then they gave an hCG injection. We waited more than a year for pregnancy, and after hCG it came! We are now six months old.”
• Victoria: “We couldn’t have a child for a long time. We've already tried everything. They studied these follicle sizes, tried different methods, stimulated me with whatever they could, and injected me with hCG, but without effect. Although the follicles matured, it still did not come out. In general, gonadotropin and nothing previously used helped us. I ignored the doctors’ recommendations and decided to adjust my weight. And it really helped me."
• Sofia: “We conceived from the first injection of hCG. Tests were taken 10 days after the injection. They immediately showed 2 stripes. It’s sad, but we were unable to maintain the pregnancy. Now we want to try again."

As you can see, the hCG injection is not a panacea. Yes, it significantly increases the chance of conception, but much depends on the individual characteristics of each woman’s body and the specific situation.

Bibliography

1. Women's consultation. Management, Editor: Radzinsky V.E. 2009 Publisher: Geotar-Media.
2. Emergency care in obstetrics and gynecology: a short guide. Serov V.N. 2008 Publisher: Geotar-Media.
3. Atlas of ultrasound diagnostics in obstetrics and gynecology. Dubile P., Benson K.B. 2009 Publisher: MEDpress-inform.